The SARS-CoV2 - ACE2 link: a physiopathological analysis
نویسندگان
چکیده
منابع مشابه
The pivotal link between ACE2 deficiency and SARS-CoV-2 infection
Angiotensin converting enzyme-2 (ACE2) receptors mediate the entry into the cell of three strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2 receptors are ubiquitous and widely expressed in the heart, vessels, gut, lung (particularly in type2 pneumocytes and macrophages), kidney, testisand brain. ACE2 is mostly bound to cell membranes and only scarcely present in the circulation in a s...
متن کاملSARS‐CoV2 Neuroinvasion Potential; Narrative Review
The outbreak of severe acute respiratory syndrome (SARS ‐ CoV-2) in December 2019 has led to the epidemic of Covid-19. Recent clinical studies have shown that parts of the nervous system; Cerebrospinal fluid (CSF) are involved in SARS-CoV-2 infection, which is associated with a variety of neurological manifestations such as headache, dizziness, and olfactory and gustatory disorders. This study ...
متن کاملPsoriasis and metabolism: a physiopathological link
Psoriasis and metabolism: a physiopathological link 1. General aim Several clinical studies have reported a strong association of psoriasis with atherosclerosis, type 2 diabetes (T2D) and metabolic syndrome, together the leading cause of mortality in western world. No physiopathological mechanism accounting for this association has been demonstrated as such a question has never been addressed i...
متن کاملIntrauterine Vertical Transmission of SARS COV2 Infection in Iranian Neonates
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) is responsible for COVID-19 disease that is transmitted from human to human via respiratory droplets and contact routes. There is no clear accurate evidence about intrauterine transmission of COVID-19 infection among newborns. Case present :The present report aims at provid ing accurate and clear information about a one-day singleton...
متن کاملIntroducing a New SYBR green Real-time PCR for Detection of SARS-CoV2 Virus Genome
Background and purpose: There are various methods for molecular detection of SARS-CoV2 genome among which, PCR-based methods are the most reliable for making diagnosis. The majority of approved PCR kits for detection of Coronavirus are based on TaqMan real-time PCR which is expensive due to incorporating fluorescent and quencher-harboring probe. The aim of this study was to design a simple and ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Vascular Cell
سال: 2020
ISSN: 2045-824X
DOI: 10.24238/13221-12-1-197